Director, Program Management (Remote Position)
Global Blood Therapeutics, Inc. (GBT)5.0
South San Francisco, CA
Job description


Position Summary:

This critical position will be responsible for providing program management leadership and expertise to support GBT’s development programs. As a Director of Program Management, this role will focus primarily on enabling the success of the strategic cross-functional Program Teams and tactical SubTeams, such as operational study teams and regulatory submissions teams.

Essential Duties and Responsibilities:

  • Translates GBT program strategy into clear action plans, integrating into both short and long-term goals and objectives
  • Partners with the Product Development Lead (PTL) and the Clinical Sub team Lead (CSTL) to define priorities and keep the teams focused and aligned, ensuring that critical project goals are understood by the sub-team representatives, and are implemented appropriately
  • Acts as PM lead on Program initiatives and sub-teams as needed, such as MAA and sNDA readiness, submission team(s)
  • Ensures effective project communications at all levels of the organization. Drives information flow and communicates project status to all stakeholders in collaboration with the CSTL, and sub-teams via oral and written communications
  • In partnership with the PDTL and sub team leads, proactively identifies potential issues and risks and work with the team to develop mitigation strategies, escalating as needed via the Head of Program Management
  • Develops and distributes agendas for meetings, facilitates effective meetings, writes meeting minutes, drives appropriate follow up on action items, and ensures appropriate escalation
  • Helps the PDT, CST and other sub-teams navigate the GBT governance structure
  • Maintains program-level project plan
  • Serves as a resource and mentors other Program Managers as appropriate
  • Leads/supports program management functional initiatives and supports cross-functional initiatives as needed
  • Spearheads additional projects as necessary to fulfill departmental objectives
  • Support PM department vision, resource and budget planning
  • Develops knowledge of current therapeutic environment and drug development trends as needed


  • Bachelor’s degree in Life Sciences or relevant field. Advanced degree (PharmD, PhD, MS, MBA, MD) preferred or strong demonstration of equivalent combination of relevant educational and professional training
  • PMP certification a plus
  • Minimum of 10 years in project and/or program management roles of increasing responsibilities
  • Minimum of 7 years managing/leading cross-functional drug development teams within a matrixed pharmaceutical, biotechnology, or medical device organization
  • Preferred: Regulatory Submission experience; Global experience with all phases of drug development
  • Extensive knowledge of project management principles and practices, including application of project management tools, methodologies, and practices
  • Experienced user and thorough working knowledge of Microsoft Project, One Pager or similar tools to support project planning and pictorial representations
  • Proficient computer skills in Microsoft Word, Outlook, Excel, and PowerPoint
  • Demonstrated ability to develop, manage and lead cross-functional teams
  • Ability to drive project plan and timelines (across multiple functional areas)
  • Proven success in goal setting, driving and operationalization of program strategy, prioritization and time management
  • Experience working with external partners
  • Hematology experience desirable but not required
  • There is the potential for this role to manage other Program Managers

Fit with GBT culture:

  • Ability to build strong relationships with co-workers of various backgrounds and expertise
  • Ability to function at a high level in a team setting whether leading the group or acting as an individual contributor
  • Values-based leadership consistent with GBT's Core Values
  • Excitement about the vision and mission of GBT
  • Flexibility
  • Integrity

NOTE: This position summary is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position may require you to work onsite or interact in person with customers of the Company and/or work onsite from time to time at the Company’s facilities. The Company requires all employees working in its facilities (including attending in-person meetings and events) to be fully vaccinated from COVID-19 (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for a disability/medical condition or sincerely-held religious belief, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. This position requires you to maintain a fully-vaccinated status against COVID-19, subject to reasonable accommodations required by applicable law. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.

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181 Oyster Point Blvd South San Francisco, CA 94080



Company Description
Global Blood Therapeutics (GBT) is a biopharmaceutical company dedicated to the discovery, development and delivery of life-changing treatments that provide hope to underserved patient communities. Founded in 2011, GBT is delivering on its goal to transform the treatment and care of sickle cell disease (SCD), a lifelong, devastating inherited blood disorder. The company has introduced Oxbryta® (voxelotor), the first FDA-approved treatment that directly inhibits sickle hemoglobin polymerization, the root cause of SCD. GBT is also advancing its pipeline program in SCD with inclacumab, a p-selectin inhibitor in development to address pain crises associated with the disease. In addition, GBT’s drug discovery teams are working on new targets to develop the next generation of treatments for SCD. To learn more, please visit and follow the company on Twitter @GBT_news.
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